Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
6-Methoxyisoquinoline-3-carboxylic acid → 3-Isoquinolinecarboxylic acid, 7-methoxy-
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | 6-Methoxyisoquinoline-3-carboxylic acid | HCID 57306949 | — |
| 반응물 | Boc-7-hydroxy-tetrahydroisoquinoline carboxylic acid | HCID 66940410 | — |
| 생성물 | 3-Isoquinolinecarboxylic acid, 7-methoxy- | HCID 10822014 | 17% |
반응 단계
0.25 g (17% in 4 steps) 7-methoxy-isoquinoline-3-carboxylic acid was prepared according to procedure described for the synthesis of 6-methoxy-isoquinoline-3-carboxylic acid (in Example 294) starting from 2.0 g (6.8 mmol) of boc-7-hydroxy-tetrahydroisoquinoline carboxylic acid using 179 mg (0.824 mmol). LCMS: 204 (M+1)+.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US08946259B2 |
| 출처 데이터셋 | uspto-grants-2015_02 |
| ORD ID | ord-caaf1206ac3c4a08961c02c983c6ee6d |
| 출처 메모 | uspto-grants-2015_02 |