HCID 66940393, compound → HCID 66940596, compound

HRID 1845063Notes

Reaction equation

HRID 1845063 reaction equation
[CH2:1]([O:8][C:9](=[O:28])[C:10]1[CH:15]=[C:14]([O:16][CH2:17][C:18]2[CH:23]=[CH:22][CH:21]=[CH:20][CH:19]=2)[CH:13]=[C:12]([NH2:24])[C:11]=1[N+:25]([O-])=O)[C:2]1[CH:7]=[CH:6][CH:5]=[CH:4][CH:3]=1>C(O)C>[CH2:1]([O:8][C:9](=[O:28])[C:10]1[CH:15]=[C:14]([O:16][CH2:17][C:18]2[CH:23]=[CH:22][CH:21]=[CH:20][CH:19]=2)[CH:13]=[C:12]([NH2:24])[C:11]=1[NH2:25])[C:2]1[CH:3]=[CH:4][CH:5]=[CH:6][CH:7]=1

Participants

3

Reactant 1

HCID 66940393HCID 66940393, compound

Product 1

HCID 66940596HCID 66940596, compound

Reagents, catalysts & solvents 1

HCID 702EthanolSolvent

Procedure

3.0 g (7.9 mmol) of 3-amino-5-benzyloxy-2-nitro-benzoic acid benzyl ester was reduced by 5.4 g (23.7 mmol) of 5 nCl2.2H2O in 30 mL of ethanol at 80° C. for 3 h to produce 2,3-diamino-5-benzyloxy-benzoic acid benzyl ester. LCMS: 350 (M+1)+.

Sources & evidence

ORD record
ord-4e2c9e0e11d44f699b6d54bdf82bcca9
Source dataset
uspto-grants-2015_02
Patent number
US08946259B2

Reaction notes

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