Ethyl 5-(hydroxymethyl)-4'-methylbiphenyl-3-carboxylate → Ethyl 5-formyl-4'-methylbiphenyl-3-carboxylate

Participants

Reaction Steps

A mixture of ethyl 5-(hydroxymethyl)-4′-methylbiphenyl-3-carboxylate (400 mg, 1.5 mmol) and manganese(IV) oxide (660 mg, 6.6 mmol) in methylene chloride (14 mL) was stirred at room temperature overnight. The reaction mixture was filtered through Celite and washed with methylene chloride. The filtrate was concentrated to afford the title compound.

Provenance & Evidence