HuagongsheHuagongshe Chemistry Print Report · For research reference only
Methyl 3-bromo-5-(hydroxymethyl)benzoate → Methyl 3-bromo-5-formylbenzoate
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Methyl 3-bromo-5-(hydroxymethyl)benzoate | HCID 11356988 | — |
| Catalyst | HCID 178418406 | HCID 178418406 | — |
| Solvent | Dichloromethane | HCID 6344 | — |
| Product | Methyl 3-bromo-5-formylbenzoate | HCID 11436457 | — |
Reaction Steps
A mixture of methyl 3-bromo-5-(hydroxymethyl)benzoate (149 mg, 0.61 mmol) and manganese(IV) oxide (529 mg, 6.08 mmol), and CH2Cl2 (3 mL) was stirred at rt overnight. The mixture was filtered through Celite and the filter cake was washed with CH2Cl2. The filtrate was concentrated to afford the title compound.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08946439B2 |
| Source dataset | uspto-grants-2015_02 |
| ORD ID | ord-793d0a7a5b774a75b219fe3f770c25ed |
| Source note | uspto-grants-2015_02 |