反应详情

Prepared analogously to example 6d with N-(3-chloro-5-fluoro-phenyl)-2-(2,2-difluoroethoxy)-5-nitro-nicotinamide (230 mg; 0.61 mmol); Ra-Ni/H2 (50 mg; 3 bar) in 8 mL. Yield: quantitative; MS: [M+H]+=346 (Cl isotope pattern); HPLC: Rt=2.1 min (Method MC-6)