HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1846377Generated: November 1, 2026
tert-Butoxy bis(dimethylamino)methane → HCID 86659826, compound
https://huagongshe.com/reaction/1846377
Participants
| Role | Name | HCID | Charge |
|---|
| Reactant | tert-Butoxy bis(dimethylamino)methane | HCID 79885 | — |
| Reactant | HCID 67454597 | HCID 67454597 | — |
| Solvent | Dimethylformamide | HCID 6228 | — |
| Product | HCID 86659826 | HCID 86659826 | 100.1% |
Reaction Steps
tert-butoxybis(dimethylamino)methane (0.50 mL, 2.30 mmol) was added to a solution of 3-(4-chlorophenyl)-2-(4-methyl-3-nitrophenyl)quinazolin-4(3H)-one (0.300 g, 0.76 mmol) in DMF (20 mL). Stirring at 50° C. for 3 hours and concentrating in vacuo afforded (E)-3-(4-chlorophenyl)-2-(4-(2-(dimethylamino)vinyl)-3-nitrophenyl)quinazolin-4(3H)-one (0.340 g, 100%).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|
| Patent number | US08952021B2 |
|---|
| Source dataset | uspto-grants-2015_02 |
|---|
| ORD ID | ord-6699dc8ccd5c46cc87a95b038b9c6de9 |
|---|
| Source note | uspto-grants-2015_02 |
|---|
