4,6-Dichloropyrimidine → HCID 86663905, compound

Participants

Reaction Conditions

Reaction Steps

820 mg (5.50 mmol) 4,6-dichloropyrimidine, 1.00 g (5.50 mmol) 6-mercapto-4-methyl-3H-benzoxazol-2-one and 5.00 mL (29.1 mmol) DIPEA were combined in 20 mL DCM and stirred overnight at 40° C. The reaction mixture was evaporated down, the residue was taken up in EtOAc and combined with sodium hydrogen carbonate solution. The precipitate formed was suction filtered, washed with copious amounts of water and dried.

Provenance & Evidence