HuagongsheHuagongshe Chemistry Print Report · For research reference only
Water → 6-(6-chloro-2-methoxypyrimidin-4-yloxy)-4-methylbenzo[d]oxazol-2(3H)-one
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Water | HCID 962 | — |
| Reactant | Potassium Carbonate | HCID 11430 | — |
| Reactant | 4,6-Dichloro-2-methoxypyrimidine | HCID 12052160 | — |
| Reactant | 6-hydroxy-4-methylbenzo[d]oxazol-2(3H)-one | HCID 66978093 | — |
| Solvent | Dimethylformamide | HCID 6228 | — |
| Product | 6-(6-chloro-2-methoxypyrimidin-4-yloxy)-4-methylbenzo[d]oxazol-2(3H)-one | HCID 86663914 | — |
Reaction Steps
0.19 g (1.01 mmol) 4,6-dichloro-2-methoxypyrimidine, 0.18 g (1.04 mmol) 6-hydroxy-4-methyl-3H-benzoxazol-2-one and 0.15 g (1.09 mmol) potassium carbonate in 1.5 mL DMF were stirred for 2 h at RT. Then water was added and the precipitate formed was suction filtered, washed and dried.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08952014B2 |
| Source dataset | uspto-grants-2015_02 |
| ORD ID | ord-66df0cd8eebb4c4fadcbb684da86dd1a |
| Source note | uspto-grants-2015_02 |