2(3H)-Benzothiazolone, 6-ethoxy-4-methyl- → 2,6-Dihydroxy-4-methylbenzothiazole

Participants

Reaction Conditions

Reaction Steps

1.00 g (4.78 mmol) 6-ethoxy-4-methylbenzo[d]thiazol-2(3H)-one and 7.00 g (60.57 mmol) pyridine hydrochloride were thoroughly mixed and stirred for 15 h under a nitrogen atmosphere at 180° C. The reaction mixture was poured onto water and extracted with ethyl acetate. The organic phase was washed with water and evaporated down i.vac. The residue was stirred with diisopropylether and suction filtered.

Provenance & Evidence