Diisopropylethylamine → HCID 178487201, compound

Participants

Reaction Steps

265 mg (0.962 mmol) 7-methoxy-3-piperidin-4-yl-1,3,4,5-tetrahydro-1,3-benzodiazepin-2-one, 250 mg (0.913 mmol) (6-chloro-pyrimidin-4-yl)-(2,7-dimethyl-1H-benzimidazol-5-yl)-amine and 1.00 mL (5.81 mmol) DIPEA were refluxed in 1.5 mL DMF. After the reaction had ended the reaction mixture was diluted with some DMF and microfiltered. The filtrate was purified by preparative HPLC. The product-containing fractions were combined and freeze-dried.

Provenance & Evidence