Diisopropylethylamine → HCID 46244316, compound

Participants

Reaction Conditions

Reaction Steps

0.10 g (0.34 mmol) 1-piperidin-4-yl-1,3-dihydroimidazo[4,5-b]pyridin-2-one-dihydrochloride, 90 mg (0.31 mmol) 6-(6-chloro-pyrimidin-4-ylamino)-3,4-dimethyl-3H-benzoxazol-2-one and 0.15 mL (0.87 mmol) DIPEA in 1.5 mL DMF were combined and stirred at 150° C. After the reaction had ended the reaction mixture was diluted with water. The precipitate formed was suction filtered, taken up in DMF and purified by preparative HPLC. The product-containing fractions were combined, evaporated down and the residue dried.

Provenance & Evidence