HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1846537Generated: November 1, 2026
Diisopropylethylamine → HCID 46244513, compound
https://huagongshe.com/reaction/1846537
Participants
| Role | Name | HCID | Charge |
|---|
| Reactant | Diisopropylethylamine | HCID 81531 | — |
| Reactant | 7-methoxy-3-(piperidin-4-yl)-4,5-dihydro-1H-benzo[d][1,3]diazepin-2(3H)-one | HCID 18356852 | — |
| Reactant | 2-[(6-Chloropyrimidin-4-yl)oxy]quinoxaline | HCID 45789043 | — |
| Solvent | Dimethylformamide | HCID 6228 | — |
| Product | HCID 46244513 | HCID 46244513 | — |
Reaction Steps
24 mg (0.087 mmol) 7-methoxy-3-piperidin-4-yl-1,3,4,5-tetrahydro-1,3-benzodiazepin-2-one, 20 mg (0.077 mmol) 2-(6-chloro-pyrimidin-4-yloxy)-quinoxaline and 0.050 mL (0.29 mmol) DIPEA were combined in 1.0 mL DMF and stirred overnight at 90° C. The reaction mixture was purified by preparative HPLC-MS. The product-containing fractions were combined and freeze-dried.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
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| Patent number | US08952014B2 |
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| Source dataset | uspto-grants-2015_02 |
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| ORD ID | ord-5d84ff266ef44202b552c190571e05cd |
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| Source note | uspto-grants-2015_02 |
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