HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1846541Generated: November 1, 2026
Diisopropylethylamine → HCID 46244598, compound
https://huagongshe.com/reaction/1846541
Participants
| Role | Name | HCID | Charge |
|---|
| Reactant | Diisopropylethylamine | HCID 81531 | — |
| Reactant | 7-methoxy-3-(piperidin-4-yl)-4,5-dihydro-1H-benzo[d][1,3]diazepin-2(3H)-one | HCID 18356852 | — |
| Reactant | HCID 86663909 | HCID 86663909 | — |
| Solvent | Dimethylformamide | HCID 6228 | — |
| Product | HCID 46244598 | HCID 46244598 | — |
Reaction Steps
75 mg (0.27 mmol) 7-methoxy-3-piperidin-4-yl-1,3,4,5-tetrahydro-1,3-benzodiazepin-2-one, 70 mg (0.26 mmol) 4-(6-chloro-pyrimidin-4-yloxy)-2-methyl-quinoline and 0.10 mL (0.58 mmol) DIPEA were combined in 1.8 mL DMF and stirred overnight at 90° C. The reaction mixture was purified by preparative HPLC-MS. The product-containing fractions were combined and freeze-dried.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|
| Patent number | US08952014B2 |
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| Source dataset | uspto-grants-2015_02 |
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| ORD ID | ord-d49d7c2628e946eab831ec4f70e1c3ec |
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| Source note | uspto-grants-2015_02 |
|---|
