Carbon Tetrachloride → HCID 67341121, compound

Participants

Reaction Steps

A mixture of 0.76 g (10 mmol) of triphenylphosphine and 1.97 g (5.00 mmol) of the above amide in carbon tetrachloride (50 mL) is stirred overnight at room temperature. The solvent is concentrated, and the residue is purified by flash silica gel chromatography to provide 1.24 g (30%) of 3-chloro-N-[5′-chloro-4-(2-chloro-ethyl)-3,4,5,6-tetrahydro-2H-[1,2′]bipyridinyl-3′-yl]-benzamide as a white solid.

Provenance & Evidence