2,5-Dichloronitrobenzene → HCID 67322174, compound

Participants

Reaction Conditions

Reaction Steps

A mixture of 0.576 g (3.00 mmol) of 2,5-dichloronitrobezene and 0.589 g (3.00 mmol) of 1-(2-piperidin-4-yl-ethyl)-piperidine in acetonitrile (5 mL) are heated at 175° C. in a microwave reactor for 30 minutes. The mixture is cooled to room temperature and concentrated under reduced pressure to provide 0.95 g (90% yield) of 1-(4-chloro-2-nitro-phenyl)-4-(2-piperidin-1-yl-ethyl)-piperidine.

Provenance & Evidence