HCID 67322174, compound → HCID 67322032, compound

Participants

Reaction Steps

To a solution of 0.351 g (1.00 mmol) of 1-(4-chloro-2-nitro-phenyl)-4-(2-piperidin-1-yl-ethyl)-piperidine dissolved in acetonitrile (5 mL) is added 0.010 g (0.01 mmol) of 10% palladium on carbon. The mixture is placed under an atmosphere of hydrogen and stirred at room temperature for 2 hours. The mixture is concentrated under reduced pressure to provide 0.322 g (quant.) of 5-chloro-2-[4-(2-piperidin-1-yl-ethyl)-piperidin-1-yl]-phenylamine.

Provenance & Evidence