Ethanol → HCID 68304347, compound

Participants

Reaction Steps

To a solution of 0.33 g (0.93 mmol) of [4-(5-cyclopropylcarbamoyl-3-nitro-pyridin-2-yl)-piperazin-1-yl]-acetic acid ethyl ester in ethanol is added 0.050 g (0.023 mmol) of 5% palladium on carbon. The mixture is placed under an atmosphere of hydrogen and stirred overnight. The mixture is filtered through a pad of diatomaceous earth and concentrated under reduced pressure to provide 0.39 g (97%) of (3′-amino-5′-cyclopropylcarbamoyl-3,4,5,6-tetrahydro-2H-[1,2′]bipyridinyl-4-yl)-acetic acid ethyl ester as a red oil.

Provenance & Evidence