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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1846730Generated: November 1, 2026

3-(Pyrrolidin-1-yl)aniline → 2-((1R,2S)-2-aminocyclohexylamino)-4-(3-(pyrrolidin-1-yl)phenylamino)pyrimidine-5-carboxamide

https://huagongshe.com/reaction/1846730

Reaction equation

Participants

RoleNameHCIDCharge
Reactant3-(Pyrrolidin-1-yl)anilineHCID 1518808—
Reactant2-[[(1R,2S)-2-aminocyclohexyl]amino]-4-[4-(1,2-oxazol-5-yl)anilino]pyrimidine-5-carboxamideHCID 46184612—
Product2-((1R,2S)-2-aminocyclohexylamino)-4-(3-(pyrrolidin-1-yl)phenylamino)pyrimidine-5-carboxamideHCID 57471902—

Reaction Steps

This compound was synthesised using the synthetic scheme described for the synthesis of compound 122, and using 3-(pyrrolidin-1-yl)aniline in step 1. MS: 396.6 (M+H).

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08952027B2
Source datasetuspto-grants-2015_02
ORD IDord-938debf722e244719c49d3d1830f0103
Source noteuspto-grants-2015_02