HCID 58548623, compound → HCID 58548667, compound

Participants

Reaction Steps

A solution of 2-(4-methoxy-cyclohexyl)-1H-benzoimidazole (500 mg, 2.17 mmol) in HI (35%) (5 mL) was heated to 90° C. for 1 h. The reaction mixture was diluted with water (20 mL) and extracted with EtOAc (2×10 mL); the organic layers was combined and washed with brine (2×10 mL), dried over Na2SO4, and concentrated to give the desired product (400 mg, 1.85 mmol, 85% yield) as brown solid.

Provenance & Evidence