HuagongsheHuagongshe Chemistry Print Report · For research reference only
N-(5-hydroxy-4-oxo-4H-pyran-2-ylmethyl)-benzene sulfonamide → 2-Chloro-N-(5-hydroxy-4-oxo-4H-pyran-2-ylmethyl)-benzenesulfonamide
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | N-(5-hydroxy-4-oxo-4H-pyran-2-ylmethyl)-benzene sulfonamide | HCID 86725691 | — |
| Reactant | N-(5-Benzyloxy-4-oxo-4H-pyran-2-ylmethyl)-2-chloro-benzenesulfonamide | HCID 86725707 | — |
| Product | 2-Chloro-N-(5-hydroxy-4-oxo-4H-pyran-2-ylmethyl)-benzenesulfonamide | HCID 86725708 | 74% |
Reaction Steps
2-Chloro-N-(5-hydroxy-4-oxo-4H-pyran-2-ylmethyl)-benzenesulfonamide (8-03) (15.0 g, crude) was synthesized as a light brown solid from N-(5-benzyloxy-4-oxo-4H-pyran-2-ylmethyl)-2-chloro-benzenesulfonamide (7-03) (26.0 g, 64.19 mmol) following the procedure described for N-(5-hydroxy-4-oxo-4H-pyran-2-ylmethyl)-benzenesulfonamide (8-01).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08952039B2 |
| Source dataset | uspto-grants-2015_02 |
| ORD ID | ord-19d8220306224f299449f70a86c905c2 |
| Source note | uspto-grants-2015_02 |