HuagongsheHuagongshe Chemistry Print Report · For research reference only
N-(5-hydroxy-4-oxo-4H-pyran-2-ylmethyl)-benzene sulfonamide → 4-Chloro-N-(5-hydroxy-4-oxo-4H-pyran-2-ylmethyl)-benzenesulfonamide
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | N-(5-hydroxy-4-oxo-4H-pyran-2-ylmethyl)-benzene sulfonamide | HCID 86725691 | — |
| Reactant | N-(5-Benzyloxy-4-oxo-4H-pyran-2-ylmethyl)-4-chloro-benzenesulfonamide | HCID 86725737 | — |
| Product | 4-Chloro-N-(5-hydroxy-4-oxo-4H-pyran-2-ylmethyl)-benzenesulfonamide | HCID 86725738 | 89.8% |
Reaction Steps
4-Chloro-N-(5-hydroxy-4-oxo-4H-pyran-2-ylmethyl)-benzenesulfonamide (8-07) (14.0 g, 89.79%) was synthesized as a light brown solid from N-(5-benzyloxy-4-oxo-4H-pyran-2-ylmethyl)-4-chloro-benzenesulfonamide (7-07) (20.0 g, 49.38 mmol) following the procedure described for N-(5-hydroxy-4-oxo-4H-pyran-2-ylmethyl)-benzenesulfonamide (8-01).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08952039B2 |
| Source dataset | uspto-grants-2015_02 |
| ORD ID | ord-17f9237808aa444490d9378f638839fd |
| Source note | uspto-grants-2015_02 |