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HRID1846891

反应详情

EQUATION

反应方程式

HRID 1846891 的结构方程式

REACTANTS

反应物

2
结构：Cn1c(C(N)S(=O)(=O)c2ccccc2)cc(=O)c(O)c1C(=O)O
HCID86725697

未命名化合物

结构：CNC(=O)c1c(OCc2ccccc2)c(=O)cc(CNS(=O)(=O)c2ccccc2C)n1C
HCID86725747

未命名化合物

PRODUCTS

生成物

1
结构：CNC(=O)c1c(O)c(=O)cc(CNS(=O)(=O)c2ccccc2C)n1C
HCID86725748

未命名化合物

收率 35.5%

PROCEDURE

实验过程

3-Hydroxy-1-methyl-4-oxo-6-[(toluene-2-sulfonylamino)-methyl]-1,4-dihydro-pyridine-2-carboxylic acid methylamide (16-02) (40.0 mg, 35.50%, purified by Prep-HPLC) was synthesized as an off white solid from 3-benzyloxy-1-methyl-4-oxo-6-[(toluene-2-sulfonylamino)-methyl]-1,4-dihydro-pyridine-2-carboxylic acid methylamide (15-02) (140.0 mg, 0.308 mmol) following the procedure described for 6-(benzene sulfonyl amino-methyl)-3-hydroxy-1-methyl-4-oxo-1,4-dihydro-pyridine-2-carboxylic acid (14-01).