HRID1846908

反应详情

EQUATION

反应方程式

REACTANTS

反应物

结构：Cn1c(C(N)S(=O)(=O)c2ccccc2)cc(=O)c(O)c1C(=O)O

HCID86725697

未命名化合物

结构：Cc1cccc(S(=O)(=O)NCc2cc(=O)c(OCc3ccccc3)c(C(=O)NC(C)C)n2C)c1

HCID86725765

未命名化合物

PRODUCTS

生成物

结构：Cc1cccc(S(=O)(=O)NCc2cc(=O)c(O)c(C(=O)NC(C)C)n2C)c1

HCID86725766

未命名化合物

收率 9.82%

PROCEDURE

实验过程

3-Hydroxy-1-methyl-4-oxo-6-[(toluene-3-sulfonylamino)-methyl]-1,4-dihydro-pyridine-2-carboxylic acid isopropylamide (18-04) (20.0 mg, 9.82%, purified by Prep-HPLC) was synthesized as a white solid from 3-benzyloxy-1-methyl-4-oxo-6-[(toluene-3-sulfonylamino)-methyl]-1,4-dihydro-pyridine-2-carboxylic acid isopropylamide (17-04) (250.0 mg, 0.518 mmol) following the procedure described for 6-(benzene sulfonyl amino-methyl)-3-hydroxy-1-methyl-4-oxo-1,4-dihydro-pyridine-2-carboxylic acid (14-01).