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HRID1846910

反应详情

EQUATION

反应方程式

HRID 1846910 的结构方程式

REACTANTS

反应物

2
结构：Cn1c(C(N)S(=O)(=O)c2ccccc2)cc(=O)c(O)c1C(=O)O
HCID86725697

未命名化合物

结构：CC(C)NC(=O)c1c(OCc2ccccc2)c(=O)cc(CNS(=O)(=O)c2cccc(Cl)c2)n1C
HCID86725767

未命名化合物

PRODUCTS

生成物

1
结构：CC(C)NC(=O)c1c(O)c(=O)cc(CNS(=O)(=O)c2cccc(Cl)c2)n1C
HCID86725768

未命名化合物

收率 38.5%

PROCEDURE

实验过程

6-[(3-Chloro-benzenesulfonylamino)-methyl]-3-hydroxy-1-methyl-4-oxo-1,4-dihydro-pyridine-2-carboxylic acid isopropylamide (18-05) (110.0 mg, 38.2%, purified by Prep-HPLC) was synthesized as a white solid from 3-benzyloxy-6-[(3-chloro-benzenesulfonylamino)-methyl]-1-methyl-4-oxo-1,4-dihydro-pyridine-2-carboxylic acid isopropylamide (17-05) (350.0 mg, 0.69 mmol) following the procedure described for 6-(benzene sulfonyl amino-methyl)-3-hydroxy-1-methyl-4-oxo-1,4-dihydro-pyridine-2-carboxylic acid (14-01).