HuagongsheHuagongshe Chemistry Print Report · For research reference only
Succinic Acid → HCID 71608767, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Succinic Acid | HCID 1110 | — |
| Reactant | benzyl N-(2-sulfamoylethyl)carbamate | HCID 11615848 | — |
| Catalyst | Palladium | HCID 23938 | — |
| Solvent | Methanol | HCID 887 | — |
| Product | HCID 71608767 | HCID 71608767 | 90% |
Reaction Steps
Take a suspension of 100 g of Cbz-Taurinamide in 1000 ml methanol, and 10% Pd/C (1.0 g) and subject to hydrogenation at 45-50 psi. Upon completion of the reaction filter the catalyst and add succinic acid (1.0 eq) to the solvent and distill off the solvent under vacuum to provide the title compound in about 90% yield as a white solid.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08952148B2 |
| Source dataset | uspto-grants-2015_02 |
| ORD ID | ord-813d380eab574ec4bedaa30dcf3265a5 |
| Source note | uspto-grants-2015_02 |