Glycine → HCID 135870670, compound

HRID 1847221Notes

Reaction equation

HRID 1847221 reaction equation
C(O[C:4]([C:6]1[C:7]([OH:29])=[C:8]2[C:22]([C:23]3[CH:28]=[CH:27][CH:26]=[CH:25][CH:24]=3)=[N:21][S:20][C:9]2=[C:10]([C:12]2[CH:17]=[CH:16][C:15]([O:18][CH3:19])=[CH:14][CH:13]=2)[N:11]=1)=[O:5])C.[NH2:30][CH2:31][C:32]([OH:34])=[O:33]>>[OH:29][C:7]1[C:6]([C:4]([NH:30][CH2:31][C:32]([OH:34])=[O:33])=[O:5])=[N:11][C:10]([C:12]2[CH:17]=[CH:16][C:15]([O:18][CH3:19])=[CH:14][CH:13]=2)=[C:9]2[S:20][N:21]=[C:22]([C:23]3[CH:24]=[CH:25][CH:26]=[CH:27][CH:28]=3)[C:8]=12

Participants

3

Reactant 2

HCID 750GlycineHCID 136344053HCID 136344053, compound

Product 1

HCID 135870670HCID 135870670, compound

Procedure

The title compound was synthesized in analogy to Example 1 from 7-(4-methoxy-phenyl)-4-hydroxy-3-phenyl-isothiazolo[5,4-c]pyridine-5-carboxylic acid ethyl ester and glycine: MS (m/z) 436.2 (M+1).

Sources & evidence

ORD record
ord-173dded7798242d8b89c83947d0441c1
Source dataset
uspto-grants-2015_02
Patent number
US08952160B2

Reaction notes

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