Glycine → HCID 135911953, compound

HRID 1847223Notes

Reaction equation

HRID 1847223 reaction equation
C(O[C:4]([C:6]1[C:7]([OH:27])=[C:8]2[C:20]([C:21]3[CH:26]=[CH:25][CH:24]=[CH:23][CH:22]=3)=[N:19][S:18][C:9]2=[C:10]([C:12]2[CH:13]=[N:14][CH:15]=[CH:16][CH:17]=2)[N:11]=1)=[O:5])C.[NH2:28][CH2:29][C:30]([OH:32])=[O:31]>>[OH:27][C:7]1[C:6]([C:4]([NH:28][CH2:29][C:30]([OH:32])=[O:31])=[O:5])=[N:11][C:10]([C:12]2[CH:13]=[N:14][CH:15]=[CH:16][CH:17]=2)=[C:9]2[S:18][N:19]=[C:20]([C:21]3[CH:22]=[CH:23][CH:24]=[CH:25][CH:26]=3)[C:8]=12

Participants

3

Reactant 2

HCID 750GlycineHCID 136335914HCID 136335914, compound

Product 1

HCID 135911953HCID 135911953, compound

Procedure

The title compound was synthesized in analogy to Example 1 from 4-hydroxy-3-phenyl-7-pyridin-3-yl-isothiazolo[5,4-c]pyridine-5-carboxylic acid ethyl ester and glycine: MS (m/z) 407.1 (M+1).

Sources & evidence

ORD record
ord-f0b1478f5c434a828149543cf4fda2e7
Source dataset
uspto-grants-2015_02
Patent number
US08952160B2

Reaction notes

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