4-(Tri-n-butylstannyl)pyridine → HCID 136344070, compound

HRID 1847226Notes

Reaction equation

HRID 1847226 reaction equation
[CH2:1]([O:3][C:4]([C:6]1[C:7]([OH:22])=[C:8]2[C:15]([C:16]3[CH:21]=[CH:20][CH:19]=[CH:18][CH:17]=3)=[N:14][S:13][C:9]2=[C:10](Br)[N:11]=1)=[O:5])[CH3:2].C([Sn](CCCC)(CCCC)[C:28]1[CH:33]=[CH:32][N:31]=[CH:30][CH:29]=1)CCC>>[CH2:1]([O:3][C:4]([C:6]1[C:7]([OH:22])=[C:8]2[C:15]([C:16]3[CH:21]=[CH:20][CH:19]=[CH:18][CH:17]=3)=[N:14][S:13][C:9]2=[C:10]([C:28]2[CH:33]=[CH:32][N:31]=[CH:30][CH:29]=2)[N:11]=1)=[O:5])[CH3:2]

Participants

3

Reactant 2

HCID 27373184-(Tri-n-butylstannyl)pyridineHCID 136344015HCID 136344015, compound

Product 1

HCID 136344070HCID 136344070, compound

Procedure

The title compound was synthesized in analogy to Example 3 from 7-bromo-4-hydroxy-3-phenyl-isothiazolo[5,4-c]pyridine-5-carboxylic acid ethyl ester and 4-(tributylstannyl)pyridine: MS (m/z) 378.1 (M+1).

Sources & evidence

ORD record
ord-a0b94bd737a9459cbeccdc71d22214a1
Source dataset
uspto-grants-2015_02
Patent number
US08952160B2

Reaction notes

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