(6-Methoxypyridin-3-yl)boronic acid → HCID 136344069, compound

HRID 1847248Notes

Reaction equation

HRID 1847248 reaction equation
[CH2:1]([O:3][C:4]([C:6]1[C:7]([OH:23])=[C:8]2[C:15]([C:16]3[CH:21]=[CH:20][C:19]([Cl:22])=[CH:18][CH:17]=3)=[N:14][S:13][C:9]2=[C:10](Br)[N:11]=1)=[O:5])[CH3:2].[CH3:24][O:25][C:26]1[CH:31]=[CH:30][C:29](B(O)O)=[CH:28][N:27]=1>>[CH2:1]([O:3][C:4]([C:6]1[C:7]([OH:23])=[C:8]2[C:15]([C:16]3[CH:21]=[CH:20][C:19]([Cl:22])=[CH:18][CH:17]=3)=[N:14][S:13][C:9]2=[C:10]([C:29]2[CH:28]=[N:27][C:26]([O:25][CH3:24])=[CH:31][CH:30]=2)[N:11]=1)=[O:5])[CH3:2]

Participants

3

Reactant 2

HCID 2734368(6-Methoxypyridin-3-yl)boronic acidHCID 136344041HCID 136344041, compound

Product 1

HCID 136344069HCID 136344069, compound

Procedure

The title compound was synthesized in analogy to Example 1 from 7-bromo-3-(4-chloro-phenyl)-4-hydroxy-isothiazolo[5,4-c]pyridine-5-carboxylic acid ethyl ester and 2-methoxy-5-pyridineboronic acid: MS (m/z) 440.1 (M−1).

Sources & evidence

ORD record
ord-666d65e0908144dd949b702a74a58008
Source dataset
uspto-grants-2015_02
Patent number
US08952160B2

Reaction notes

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