1-Naphthaleneboronic acid → HCID 136343983, compound

HRID 1847252Notes

Reaction equation

HRID 1847252 reaction equation
[CH2:1]([O:3][C:4]([C:6]1[C:7]([OH:23])=[C:8]2[C:15]([C:16]3[CH:21]=[CH:20][C:19]([Cl:22])=[CH:18][CH:17]=3)=[N:14][S:13][C:9]2=[C:10](Br)[N:11]=1)=[O:5])[CH3:2].[C:24]1(B(O)O)[C:33]2[C:28](=[CH:29][CH:30]=[CH:31][CH:32]=2)[CH:27]=[CH:26][CH:25]=1>>[CH2:1]([O:3][C:4]([C:6]1[C:7]([OH:23])=[C:8]2[C:15]([C:16]3[CH:21]=[CH:20][C:19]([Cl:22])=[CH:18][CH:17]=3)=[N:14][S:13][C:9]2=[C:10]([C:32]2[C:33]3[C:28](=[CH:27][CH:26]=[CH:25][CH:24]=3)[CH:29]=[CH:30][CH:31]=2)[N:11]=1)=[O:5])[CH3:2]

Participants

3

Reactant 2

HCID 2545321-Naphthaleneboronic acidHCID 136344041HCID 136344041, compound

Product 1

HCID 136343983HCID 136343983, compound

Procedure

The title compound was synthesized in analogy to Example 1 from 7-bromo-3-(4-chloro-phenyl)-4-hydroxy-isothiazolo[5,4-c]pyridine-5-carboxylic acid ethyl ester and 1-naphthylboronic acid: MS (m/z) 461.0 (M+1).

Sources & evidence

ORD record
ord-c26c98d4d2cf4240b880cad6da3ff8c7
Source dataset
uspto-grants-2015_02
Patent number
US08952160B2

Reaction notes

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