Glycine → HCID 135950367, compound

HRID 1847266Notes

Reaction equation

HRID 1847266 reaction equation
C(O[C:4]([C:6]1[C:7]([OH:28])=[C:8]2[C:20]([C:21]3[CH:26]=[CH:25][CH:24]=[CH:23][C:22]=3[F:27])=[N:19][S:18][C:9]2=[C:10]([C:12]2[CH:17]=[CH:16][CH:15]=[CH:14][CH:13]=2)[N:11]=1)=[O:5])C.[NH2:29][CH2:30][C:31]([OH:33])=[O:32]>>[F:27][C:22]1[CH:23]=[CH:24][CH:25]=[CH:26][C:21]=1[C:20]1[C:8]2[C:9](=[C:10]([C:12]3[CH:13]=[CH:14][CH:15]=[CH:16][CH:17]=3)[N:11]=[C:6]([C:4]([NH:29][CH2:30][C:31]([OH:33])=[O:32])=[O:5])[C:7]=2[OH:28])[S:18][N:19]=1

Participants

3

Reactant 2

HCID 750GlycineHCID 136413565HCID 136413565, compound

Product 1

HCID 135950367HCID 135950367, compound

Procedure

The title compound was synthesized in analogy to Example 1 from 3-(2-fluoro-phenyl)-4-hydroxy-7-phenyl-isothiazolo[5,4-c]pyridine-5-carboxylic acid ethyl ester and glycine: MS (m/z) 422.0 (M−1).

Sources & evidence

ORD record
ord-1ff6b9d9dec04ac6ba6ed4243a97fed2
Source dataset
uspto-grants-2015_02
Patent number
US08952160B2

Reaction notes

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