Tetramethyltin → HCID 136344024, compound

HRID 1847269Notes

Reaction equation

[CH2:1]([O:3][C:4]([C:6]1[C:7]([OH:23])=[C:8]2[C:15]([C:16]3[CH:21]=[CH:20][CH:19]=[CH:18][C:17]=3[F:22])=[N:14][S:13][C:9]2=[C:10](Br)[N:11]=1)=[O:5])[CH3:2].[CH3:24][Sn](C)(C)C>>[CH2:1]([O:3][C:4]([C:6]1[C:7]([OH:23])=[C:8]2[C:15]([C:16]3[CH:21]=[CH:20][CH:19]=[CH:18][C:17]=3[F:22])=[N:14][S:13][C:9]2=[C:10]([CH3:24])[N:11]=1)=[O:5])[CH3:2]

Participants

Reactant 2

HCID 11661Tetramethyltin

HCID 136344035HCID 136344035, compound

Product 1

HCID 136344024HCID 136344024, compound

Procedure

The title compound was synthesized in analogy Example 28 from 7-bromo-3-(2-fluoro-phenyl)-4-hydroxy-isothiazolo[5,4-c]pyridine-5-carboxylic acid ethyl ester and tetramethyltin: MS (m/z) 333.2 (M+1).

Sources & evidence

ORD record: ord-3e0aca0a37b7442589591f780c42f3f3
Source dataset: uspto-grants-2015_02
DOI: 10.6084/m9.figshare.5104873.v1
Patent number: US08952160B2

Reaction notes

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