Glycine → HCID 135950378, compound

HRID 1847274Notes

Reaction equation

HRID 1847274 reaction equation
C(O[C:6]([C:8]1[C:9]([OH:24])=[C:10]2[C:22]([CH3:23])=[N:21][S:20][C:11]2=[C:12]([C:14]2[CH:19]=[CH:18][CH:17]=[CH:16][N:15]=2)[N:13]=1)=[O:7])CCC.[NH2:25][CH2:26][C:27]([OH:29])=[O:28]>>[OH:24][C:9]1[C:8]([C:6]([NH:25][CH2:26][C:27]([OH:29])=[O:28])=[O:7])=[N:13][C:12]([C:14]2[CH:19]=[CH:18][CH:17]=[CH:16][N:15]=2)=[C:11]2[S:20][N:21]=[C:22]([CH3:23])[C:10]=12

Participants

3

Reactant 2

HCID 750GlycineHCID 136344038HCID 136344038, compound

Product 1

HCID 135950378HCID 135950378, compound

Procedure

The title compound was synthesized in analogy Example 1 from 4-hydroxy-3-methyl-7-pyridin-2-yl-isothiazolo[5,4-c]pyridine-5-carboxylic acid butyl ester and glycine: MS (m/z) 345.2 (M+1).

Sources & evidence

ORD record
ord-73a29e01bf4f45ab894e07ef0a3d6840
Source dataset
uspto-grants-2015_02
Patent number
US08952160B2

Reaction notes

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