Glycine → HCID 135950391, compound

HRID 1847280Notes

Reaction equation

C(O[C:6]([C:8]1[N:13]=[C:12]([C:14]2[CH:19]=[N:18][CH:17]=[CH:16][N:15]=2)[C:11]2[C:20]([CH3:23])=[N:21][S:22][C:10]=2[C:9]=1[OH:24])=[O:7])CCC.[NH2:25][CH2:26][C:27]([OH:29])=[O:28]>>[OH:24][C:9]1[C:10]2[S:22][N:21]=[C:20]([CH3:23])[C:11]=2[C:12]([C:14]2[CH:19]=[N:18][CH:17]=[CH:16][N:15]=2)=[N:13][C:8]=1[C:6]([NH:25][CH2:26][C:27]([OH:29])=[O:28])=[O:7]

Participants

Reactant 2

HCID 750Glycine

HCID 136404173HCID 136404173, compound

Product 1

HCID 135950391HCID 135950391, compound

Procedure

The title compound was synthesized in analogy Example 3 from 7-hydroxy-3-methyl-4-pyrazin-2-yl-isothiazolo[4,5-c]pyridine-6-carboxylic acid butyl ester and glycine: MS (m/z) 346.1 (M+1).

Sources & evidence

ORD record: ord-ad2790b3b7384aeea72d548e1ea9cec4
Source dataset: uspto-grants-2015_02
DOI: 10.6084/m9.figshare.5104873.v1
Patent number: US08952160B2

Reaction notes

Loading…