Glycine → HCID 44193983, compound

HRID 1847292Notes

Reaction equation

C(O[C:6]([C:8]1[N:13]=[C:12]([CH2:14][CH3:15])[C:11]2[C:16]([CH3:19])=[N:17][S:18][C:10]=2[C:9]=1[OH:20])=[O:7])CCC.[NH2:21][CH2:22][C:23]([OH:25])=[O:24]>>[CH2:14]([C:12]1[C:11]2[C:16]([CH3:19])=[N:17][S:18][C:10]=2[C:9]([OH:20])=[C:8]([C:6]([NH:21][CH2:22][C:23]([OH:25])=[O:24])=[O:7])[N:13]=1)[CH3:15]

Participants

Reactant 2

HCID 750Glycine

HCID 68628549HCID 68628549, compound

Product 1

HCID 44193983HCID 44193983, compound

Procedure

The title compound was synthesized in analogy to Example 1 from 4-ethyl-7-hydroxy-3-methyl-isothiazolo[4,5-c]pyridine-6-carboxylic acid butyl ester and glycine: MS (m/z) 296.2 (M+1).

Sources & evidence

ORD record: ord-98a220cd22d449809d164216f4fc4eb8
Source dataset: uspto-grants-2015_02
DOI: 10.6084/m9.figshare.5104873.v1
Patent number: US08952160B2

Reaction notes

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