Dimethylformamide → (E)-2-(5-fluoro-2,4-dinitrophenyl)-N,N-dimethylethenamine

HRID 1847477ノート

反応式

HRID 1847477 の反応式
[F:1][C:2]1[CH:7]=[C:6]([CH3:8])[C:5]([N+:9]([O-:11])=[O:10])=[CH:4][C:3]=1[N+:12]([O-:14])=[O:13].C[C:16]([N:18]([CH3:20])[CH3:19])=O.CN(C=O)C>O>[F:1][C:2]1[C:3]([N+:12]([O-:14])=[O:13])=[CH:4][C:5]([N+:9]([O-:11])=[O:10])=[C:6](/[CH:8]=[CH:16]/[N:18]([CH3:20])[CH3:19])[CH:7]=1

参加物

5

反応物 3

HCID 6228DimethylformamideHCID 31374DimethylacetamideHCID 5207051-Fluoro-5-methyl-2,4-dinitrobenzene

生成物 1

HCID 15022335(E)-2-(5-fluoro-2,4-dinitrophenyl)-N,N-dimethylethenamine収率 63%

試薬・触媒・溶媒 1

HCID 962Water溶媒

反応条件

温度
100 °C

実験手順

A mixture of 1-fluoro-5-methyl-2,4-dinitro-benzene (10 g, 50 mmol), DMA (12 g, 100 mmol) and DMF (50 mL) was heated at 100° C. for 4 h. The solution was cooled and poured into water. The precipitated red solid was collected, washed with water, and dried to give (E)-2-(5-fluoro-2,4-dinitrophenyl)-N,N-dimethylethenamine (8.0 g, 63%).

後処理

  1. temperatureThe solution was cooled
  2. customThe precipitated red solid was collected
  3. washwashed with water
  4. customdried

出典と根拠

ORDレコード
ord-7bba44fce6764bd9a5746d77d4576040
出典データセット
uspto-grants-2015_02
特許番号
US08952050B2

反応ノート

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