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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1847619Generated: November 2, 2026

Benzyl isocyanate → HCID 66778751, compound

https://huagongshe.com/reaction/1847619

Reaction equation

Participants

RoleNameHCIDCharge
ReactantBenzyl isocyanateHCID 76639—
ReactantDiisopropylethylamineHCID 81531—
ReactantHCID 56847101HCID 56847101—
SolventDimethylformamideHCID 6228—
ProductHCID 66778751HCID 66778751—

Reaction Steps

To a vial containing benzyl isocyanate (0.0166 g, 0.125 mmol), was added methyl 5,6,7,8-tetrahydro-1,6-naphthyridine-2-carboxylate hydrochloride (0.0220 g, 0.0962 mmol), DIPEA (0.0586 mL, 0.337 mmol) and DMF (2 mL). The resulting solution was then shaken at rt for 13 h and then concentrated to give methyl 6-(benzylcarbamoyl)-5,6,7,8-tetrahydro-1,6-naphthyridine-2-carboxylate.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08952163B2
Source datasetuspto-grants-2015_02
ORD IDord-93374b812bee43179258991537c1f28d
Source noteuspto-grants-2015_02