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HRID18477

反应详情

EQUATION

反应方程式

HRID 18477 的结构方程式

REACTANTS

反应物

3
结构：O=C1CCCOC1
HCID90109

2H-Pyran-3(4H)-one, dihydro-

C5H8O2

结构：O=C(Cl)c1cc(F)c(F)cc1F
HCID145164

2,4,5-Trifluorobenzoyl chloride

C7H2ClF3O

结构：CC(C)(C)OC(=O)N1CCc2[nH]nc(-c3ccc(F)c(F)c3)c2C1
HCID59345327

未命名化合物

PRODUCTS

生成物

1
结构：Fc1cc(F)c(-c2n[nH]c3c2CCOC3)cc1F
HCID59345342

未命名化合物

PROCEDURE

实验过程

Intermediate 16D was prepared according to the procedure for the synthesis of intermediate 15 by replacing 1-Boc-4-piperidone with dihydro-2H-pyran-3(4H)-one, and replacing 3,4-difluorobenzoyl chloride with 2,4,5-trifluorobenzoyl chloride. LCMS (+ESI) m/z=255 [M+H]+.