HuagongsheHuagongshe Chemistry Print Report · For research reference only
Ethyl pyruvate → ethyl (2E)-2-[(3-nitrophenyl)hydrazinylidene]propanoate
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Ethyl pyruvate | HCID 12041 | — |
| Reactant | 3-Nitrophenylhydrazinium(1+) chloride | HCID 5464285 | — |
| Solvent | Ethanol | HCID 702 | — |
| Product | ethyl (2E)-2-[(3-nitrophenyl)hydrazinylidene]propanoate | HCID 5357576 | — |
Reaction Steps
(3-Nitrophenyl)hydrazine hydrochloride (30 g, 0.16 mol) and 2-oxo-propionic acid ethyl ester (22 g, 0.19 mol) were dissolved in ethanol (300 mL). The mixture was stirred at room temperature for 4 h before the solvent was evaporated under reduced pressure to give (E)-ethyl 2-(2-(3-nitrophenyl)hydrazono)propanoate, which was used directly in the next step.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08952049B2 |
| Source dataset | uspto-grants-2015_02 |
| ORD ID | ord-91f61486901a46279c13c6438344558f |
| Source note | uspto-grants-2015_02 |