HuagongsheHuagongshe Chemistry Print Report · For research reference only
1-(1,3-Dioxaindan-5-yl)cyclopropane-1-carboxylic acid → (S)-1-(benzo[d][1,3]dioxol-5-yl)-N-(2-tert-butyl-1-(2,3-dihydroxypropyl)-6-fluoro-1H-indol-5-yl)cyclopropanecarboxamide
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 1-(1,3-Dioxaindan-5-yl)cyclopropane-1-carboxylic acid | HCID 14349608 | — |
| Reactant | 2-Tert-butyl-6-fluoro-5-nitro-1H-indole | HCID 53421186 | — |
| Product | (S)-1-(benzo[d][1,3]dioxol-5-yl)-N-(2-tert-butyl-1-(2,3-dihydroxypropyl)-6-fluoro-1H-indol-5-yl)cyclopropanecarboxamide | HCID 46199865 | — |
Reaction Steps
(S)-1-(benzo[d][1,3]dioxol-5-yl)-N-(2-tert-butyl-1-(2,3-dihydroxypropyl)-6-fluoro-1H-indol-5-yl)cyclopropanecarboxamide was prepared using an experimental procedure similar to Example 72 from 1-(benzo[d][1,3]dioxol-5-yl)cyclopropanecarboxylic acid and 2-tert-butyl-6-fluoro-5-nitro-1H-indol.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08952049B2 |
| Source dataset | uspto-grants-2015_02 |
| ORD ID | ord-e4a47f69b5bb41a28a138b1e3b780eb0 |
| Source note | uspto-grants-2015_02 |