HuagongsheHuagongshe Chemistry Print Report · For research reference only
4-Bromo-2-(methylthio)benzo[d]thiazole-6-carbonitrile → (4-Bromo-2-(methylthio)benzo[d]thiazol-6-yl)methanamine
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 4-Bromo-2-(methylthio)benzo[d]thiazole-6-carbonitrile | HCID 86681164 | — |
| Reactant | 5-Fluoro-2-(methylthio)benzo[d]thiazole-6-carbonitrile | HCID 86681168 | — |
| Product | (4-Bromo-2-(methylthio)benzo[d]thiazol-6-yl)methanamine | HCID 86681167 | — |
Reaction Steps
(4-Bromo-2-(methylthio)benzo[d]thiazol-6-yl)methanamine was synthesized as a clear oil (794 mg, 79%) using a procedure analogous to that described in Step 3 of Example 154, substituting 4-bromo-2-(methylthio)benzo[d]thiazole-6-carbonitrile from the previous step for 5-fluoro-2-(methylthio)benzo[d]thiazole-6-carbonitrile used in Example 154. LCMS (ESI) m/z 288, 290 (M+H)+.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08952058B2 |
| Source dataset | uspto-grants-2015_02 |
| ORD ID | ord-c8c7b5621af843428506af42b67c8991 |
| Source note | uspto-grants-2015_02 |