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HRID1848372

反应详情

EQUATION

反应方程式

HRID 1848372 的结构方程式

REACTANTS

反应物

3
结构：O=C(O)CCN1C(=O)c2ccccc2C1=O
HCID76859

1,3-Dihydro-1,3-dioxo-2H-isoindole-2-propionic acid

C11H9NO4

结构：CC(C)(C)OC(=O)NCCOCCOCCN
HCID9881394

tert-Butyl {2-[2-(2-aminoethoxy)ethoxy]ethyl}carbamate

C11H24N2O4

结构：CC1(C)OC(=O)/C(=C/C(=O)NCCCc2ccc(Cl)c(Cl)c2)O1
HCID21947512

未命名化合物

PRODUCTS

生成物

1
结构：CC(C)(C)OC(=O)NCCOCCOCCNC(=O)CCN1C(=O)c2ccccc2C1=O
HCID86728174

未命名化合物

收率 97.3%

PROCEDURE

实验过程

By appropriate application of the method used to synthesize Intermediate 5, tert-butyl 2-(2-(2-aminoethoxy)ethoxy)ethylcarbamate (400 mg, 1.6 mmol) and 3-(1,3-dioxoisoindolin-2-yl)propanoic acid (388 mg, 1.8 mmol) were combined to provide Intermediate 7A (700 mg, 87% yield). HPLC/MS (Method C) RT=2.80 min, [M+H]+ 450.