HuagongsheHuagongshe Chemistry Print Report · For research reference only
(Z)-N-(3-(3,4-dichlorophenyl)propyl)-2-(2,2-dimethyl-5-oxo-1,3-dioxolan-4-ylidene)acetamide → (Z)-N-((E)-4-(3,4-dichlorophenyl)but-3-enyl)-2-(2,2-dimethyl-5-oxo-1,3-dioxolan-4-ylidene)acetamide
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | (Z)-N-(3-(3,4-dichlorophenyl)propyl)-2-(2,2-dimethyl-5-oxo-1,3-dioxolan-4-ylidene)acetamide | HCID 21947512 | — |
| Reactant | (E)-4-(3,4-dichlorophenyl)but-3-en-1-amine | HCID 63969265 | — |
| Product | (Z)-N-((E)-4-(3,4-dichlorophenyl)but-3-enyl)-2-(2,2-dimethyl-5-oxo-1,3-dioxolan-4-ylidene)acetamide | HCID 89477795 | 54% |
Reaction Steps
By appropriate application of method used to synthesize Intermediate 5, Intermediate 6 (41 mg, 0.19 mmol) was converted to Example 143 A (38 mg, 0.10 mmol, 54% yield). HPLC/MS (Method D) RT=1.06 min, [M+H]+ 370.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08952180B2 |
| Source dataset | uspto-grants-2015_02 |
| ORD ID | ord-7d9d68b6ff9d4b53820b78a1471dd53f |
| Source note | uspto-grants-2015_02 |