HuagongsheHuagongshe Chemistry Print Report · For research reference only
Potassium vinyltrifluoroborate → HCID 66643952, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Potassium vinyltrifluoroborate | HCID 23679353 | — |
| Reactant | HCID 66643986 | HCID 66643986 | — |
| Catalyst | Bis(cyclopenta-1,4-dien-1-yl(diphenyl)phosphane);dichloropalladium;iron(2+) | HCID 178418228 | — |
| Solvent | Ethanol | HCID 702 | — |
| Product | HCID 66643952 | HCID 66643952 | — |
Reaction Steps
A mixture of 5-bromo-4-ethyl-2-benzofuran-1(3H)-one (1.81 g, 7.51 mmol), potassium vinyltrifluoroborate (1.21 g, 9.01 mmol) and Pd(dppf)Cl2 (200 mg) in 20 mL of TEA and 20 mL of EtOH was heated to reflux under N2 overnight and then concentrated. The resulting material was purified by column chromatography to give 4-ethyl-5-vinyl-2-benzofuran-1(3H)-one.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08952166B2 |
| Source dataset | uspto-grants-2015_02 |
| ORD ID | ord-cb7d12901ac64be0b43e23c47af67893 |
| Source note | uspto-grants-2015_02 |