HCID 86673665, compound → HCID 44440598, compound

HRID 1848672Notes

Reaction equation

HRID 1848672 reaction equation
[C:1]([O:4][CH2:5][CH:6]([O:13][C:14](=[O:16])[CH3:15])[C:7](=[N+]=[N-])[C:8](=[O:10])[CH3:9])(=[O:3])[CH3:2].CC(C)=[O:19].CC1(C)OO1>CC(C)=O>[C:1]([O:4][CH2:5][CH:6]([O:13][C:14](=[O:16])[CH3:15])[C:7](=[O:19])[C:8](=[O:10])[CH3:9])(=[O:3])[CH3:2]

Participants

4

Reactant 2

HCID 86673665HCID 86673665, compoundHCID 86673667HCID 86673667, compound

Product 1

HCID 44440598HCID 44440598, compound

Reagents, catalysts & solvents 1

HCID 180AcetoneSolvent

Procedure

To a solution of methyl diazo diacetate 7 (20 mg, 0.088 mmol) in acetone (1 mL) was added dimethyldioxirane acetone solution (2.5 mL, ca. 0.07-0.09 M). The resulting mixture was stirred for 1 h and solvent and excess reagents were removed under reduced pressure to obtain 19 as bright yellow oil (yield=19 mg, quantitative).

Workup

  1. customsolvent and excess reagents were removed under reduced pressure

Sources & evidence

ORD record
ord-8d179e02fab747f78ba6406bbf75b406
Source dataset
uspto-grants-2015_02
Patent number
US08952192B2

Reaction notes

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