HCID 86673667, compound → HCID 86673668, compound

HRID 1848673Notes

Reaction equation

HRID 1848673 reaction equation
[C:1]([O:6][CH2:7][CH:8]([O:15][C:16](=[O:20])[CH2:17][CH2:18][CH3:19])[C:9](=[N+]=[N-])[C:10](=[O:12])[CH3:11])(=[O:5])[CH2:2][CH2:3][CH3:4].CC(C)=[O:23].CC1(C)OO1>CC(C)=O>[C:1]([O:6][CH2:7][CH:8]([O:15][C:16](=[O:20])[CH2:17][CH2:18][CH3:19])[C:9](=[O:23])[C:10](=[O:12])[CH3:11])(=[O:5])[CH2:2][CH2:3][CH3:4]

Participants

4

Reactant 2

HCID 86673667HCID 86673667, compoundHCID 86673669HCID 86673669, compound

Product 1

HCID 86673668HCID 86673668, compound

Reagents, catalysts & solvents 1

HCID 180AcetoneSolvent

Procedure

To a solution of methyl diazo dibutyrate 8 (23 mg, 0.081 mmol) in acetone (1 mL) was added dimethyldioxirane acetone solution (2.5 mL, ca. 0.07-0.09 M). The resulting mixture was stirred for 1 h and solvent and excess reagents were removed under reduced pressure to obtain 20 as bright yellow oil (yield=22 mg, quantitative).

Workup

  1. customsolvent and excess reagents were removed under reduced pressure

Sources & evidence

ORD record
ord-3fc1459a98474b5f85d012c8d1b7c25e
Source dataset
uspto-grants-2015_02
Patent number
US08952192B2

Reaction notes

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