HCID 86673667, compound → HCID 86673674, compound

HRID 1848675Notes

Reaction equation

HRID 1848675 reaction equation
[C:1]([O:8][CH2:9][CH:10]([O:17][C:18](=[O:24])[CH2:19][CH2:20][CH2:21][CH2:22][CH3:23])[C:11](=[N+]=[N-])[C:12](=[O:14])[CH3:13])(=[O:7])[CH2:2][CH2:3][CH2:4][CH2:5][CH3:6].CC(C)=[O:27].CC1(C)OO1>CC(C)=O>[C:1]([O:8][CH2:9][CH:10]([O:17][C:18](=[O:24])[CH2:19][CH2:20][CH2:21][CH2:22][CH3:23])[C:11](=[O:27])[C:12](=[O:14])[CH3:13])(=[O:7])[CH2:2][CH2:3][CH2:4][CH2:5][CH3:6]

Participants

4

Reactant 2

HCID 86673667HCID 86673667, compoundHCID 86673675HCID 86673675, compound

Product 1

HCID 86673674HCID 86673674, compound

Reagents, catalysts & solvents 1

HCID 180AcetoneSolvent

Procedure

To a solution of methyl diazo dihexanoate 10 (38 mg, 0.112 mmol) in acetone (1 mL) was added dimethyldioxirane acetone solution (2.5 mL, ca. 0.07-0.09 M). The resulting mixture was stirred for 1 h and solvent and excess reagents were removed under reduced pressure to obtain 22 as bright yellow oil (yield=36.8 mg, quantitative).

Workup

  1. customsolvent and excess reagents were removed under reduced pressure

Sources & evidence

ORD record
ord-23f59f6dbf8046d09a6008370aed242b
Source dataset
uspto-grants-2015_02
Patent number
US08952192B2

Reaction notes

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