反应详情

A solution of (6-hydroxy-1-benzofuran-3-yl)acetic acid (S)-2-amino-1,1-diphenylpropan-1-ol salt (19.64 g) and dichloro[(+)-1,2-bis((2R,5R)-2,5-diisopropylphosphorano)benzene]ruthenium (II)-N,N-dimethylformamide complex (2.3 mg) in dehydrated methanol (90 ml) was stirred at 35° C. for 22 hr under a hydrogen atmosphere (1.1 MPa). To the reaction solution was added methanol (9 mL) to give a methanol solution of the title compound. 81.3% de