反应详情

A racemate (0.05 g) of (6-hydroxy-2,3-dihydro-1-benzofuran-3-yl)acetic acid was charged, a mixed solvent of methanol/isopropyl alcohol (1/4) was added, and the racemate was dissolved. (S)-2-Amino-1,1-diphenylpropan-1-ol (0.059 g, 1 eq) was added thereto, and the mixture was stirred at room temperature for 12 hr. The precipitated crystals were collected by filtration to give the title compound (0.037 g). 87.8% de

1. dissolutionthe racemate was dissolved
2. filtrationThe precipitated crystals were collected by filtration