HuagongsheHuagongshe Chemistry Print Report · For research reference only
Dihydrocoumarin → 3-(2-hydroxyphenyl)-N,N-dimethylpropanamide
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Dihydrocoumarin | HCID 660 | — |
| Reactant | Dimethylamine | HCID 674 | — |
| Solvent | Tetrahydrofuran | HCID 8028 | — |
| Product | 3-(2-hydroxyphenyl)-N,N-dimethylpropanamide | HCID 25584712 | — |
Reaction Steps
A solution of chroman-2-one (444 mg) in THF (1 mL) was treated with dimethylamine (7.5 mL) and stirred at room temperature for 5 hours. The solution was concentrated. The concentrate was filtered through a small pad of silica gel.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08952157B2 |
| Source dataset | uspto-grants-2015_02 |
| ORD ID | ord-ada01e26ba4f4331ae5dd78024b7afe6 |
| Source note | uspto-grants-2015_02 |